# Canitide VITAL · Metabolic vitality & stamina

Mitochondrial signaling for the senior slowdown. Metabolic vitality & stamina. MOTS-c, dosed to your dog’s weight. From $99; reserve now, pay when it ships.

Canonical: https://canitide.com/products/canitide-vital/
Updated: 2026-10-13

Mitochondrial signaling for the senior slowdown. MOTS-c is the mitochondrial-derived peptide studied for exercise capacity, metabolic homeostasis, and age-related physical decline. For seniors losing their engine.

- **Actives:** MOTS-c 10 mg
- **Protocol:** 3× per week · 8-week cycle
- **Formats:** Pen cartridge $99 (Club $84); Starter Kit $129

## Who it’s for

- Senior dogs whose walks keep getting shorter
- Dogs carrying extra weight alongside LEAN
- Sport dogs building an off-season base
- Metabolically sluggish breeds (with your vet)

## Dosing by weight

| Weight band | Per dose | Per dose (mcg) | Per week | Cartridge lasts | Club cadence |
|---|---|---|---|---|---|
| Small (under 20 lb) | 10 units | 330 mcg | 30 units | ~10 weeks | every 8 weeks |
| Medium (20–50 lb) | 15 units | 495 mcg | 45 units | ~6 weeks | every 6 weeks |
| Large (50–90 lb) | 20 units | 660 mcg | 60 units | ~5 weeks | every 4 weeks |
| Giant (90 lb and up) | 25 units | 825 mcg | 75 units | ~4 weeks | every 4 weeks |

## The research

- The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Lee C et al. Cell Metab 2015 (mouse)
- MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis. Reynolds JC et al. Nat Commun 2021 (mouse (aged))