Dosing / GHK-Cu
Dosing by peptide
GHK-Cu for dogs: dosage chart by weight
GHK-Cu is a copper-binding tripeptide studied for collagen production, skin remodeling and wound support. It is one of the few peptides with genuine canine research: open-wound healing work in dogs in the 1990s.
Canitide COAT · Daily · 8-week cycle, then maintenance
GHK-Cu dose by weight band.
One pen unit is 0.01 mL and carries about 167 mcg of GHK-Cu. The bands are set from the mg/kg ranges in the animal research, rounded to whole units.
| Weight band | Per dose | Per dose (mcg) | Per week | Cartridge lasts | Club cadence |
|---|---|---|---|---|---|
| Small (under 20 lb) | 4 units | 668 mcg | 28 units | ~10 weeks | every 8 weeks |
| Medium (20–50 lb) | 6 units | 1002 mcg | 42 units | ~7 weeks | every 6 weeks |
| Large (50–90 lb) | 8 units | 1336 mcg | 56 units | ~5 weeks | every 4 weeks |
| Giant (90 lb and up) | 10 units | 1670 mcg | 70 units | ~4 weeks | every 4 weeks |
Cartridges hold 300 usable units after the 2-unit prime. Missed a dose? Skip it and continue; never double up.
Canitide products are sold for research purposes and are not FDA-approved drugs. Talk to your veterinarian before starting any protocol, and bring the dosing card.
Your dog
Enter a weight, get the number.
Owners use it for dull coats, senior skin and dogs prone to hot spots. Canitide COAT is 50 mg of GHK-Cu in one pre-mixed cartridge, dosed daily for eight weeks.
Reserve Canitide COATIf you use a vial
A 50 mg vial of GHK-Cu in 3 mL of bacteriostatic water is 16.7 mg/mL, the same concentration as a COAT cartridge. On a U-100 insulin syringe one unit is also 0.01 mL, so the chart above reads the same. What changes with the pen: no reconstitution, no drawing up, a sterility-tested cartridge, a 32G × 4 mm needle, and a dial you cannot misread. The pen versus vial kits.
Questions about GHK-Cu for dogs
What is the GHK-Cu dose for dogs?
COAT doses 4, 6, 8 or 10 units a day by weight band (under 20 lb, 20–50 lb, 50–90 lb, 90 lb and up). One unit of COAT carries about 167 mcg of GHK-Cu.
Is GHK-Cu safe for dogs?
GHK-Cu has canine wound-healing research and a long record of topical use in people, but no controlled canine trial of injectable use. The usual cautions apply: talk to your vet, watch the injection site, stop if anything worries you.
Can I use GHK-Cu on the skin instead?
A topical COAT Serum is on the Canitide roadmap for summer 2027. Today COAT is a cartridge for the pen.
How long until the coat changes?
Owners typically report changes over the eight-week cycle, not in the first days. Track it with photos in Fieldnotes so you and your vet can see it rather than remember it.
The research
Primary sources only, each labeled with the model it was studied in.
- reviewRegenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene DataPickart L, Margolina A · Int J Mol Sci 2018
- dogsEvaluation of multipeptide copper complex medications on open wound healing in dogsSwaim SF et al. · J Am Anim Hosp Assoc 1993
- reviewThe human tri-peptide GHK and tissue remodelingPickart L · J Biomater Sci Polym Ed 2008